Meclizine or Meclizine Hydrochloride is used as a commonly used molecule to control the symptoms of vertiginous feeling or imbalance to control nausea & vomiting which usually associated with vertigo
Meclizine is available under different brand names
Antivert, Meni -D, Meclozine, Bonine, Dramamine, VertiCalm, D-Vert, Meclicot, Medivert, Driminate
Meclizine is an antihistamine drug with property to relieve nausea ,vomiting .cramps in the abdomem. Antihismines act by reducing the effect of histamine that causes actions like constriction of airways ,dilation of blood vessels there by increasing the permeability of blood vessels.
Due to its action on the CNS as it has an anticholinergic effect & Acetylcholine.gets suppresed
Meclizine HCL causes vestibular depression of hair cells in the labyrinth and hence the vertiginous feeling of rotation &/or rotation .
Because of the depression of brain activities and anti emetic actions the complaints of nausea &.vomiting during Travel sickness are immediately relieved
Meclizine is available in different strengths 12.5 mg to 50 mg
Meclizine tablet is recommended an hour before travelling 12.5mg-50 mg The dosage can be repeated 8 hourly for Adults suffering from Motion Sickness & vertigo
In children below 12 years & elderly 65 years plus avoid using Meclizine ta
Meclizine can be safely taken during pregnancy and lactation.
Avoid extra or repeated doses as it can cause extra pyramidal symptoms
Sedation is associated with Meclizine Hence avoid during working hours or doing heavy physical activities No driving &.Alcohol consumption is strictly contraindicated
Gastro intestinal Disturbances
Impaired cognitive skills
Feeling of getting tired
Reduced blood pressure
Odema & Swelling of Facial Structures
Side effects get reduced once the drug is discontinued. If they do not get reduced or in case get severe, consult the doctor immediately. Meclizine Hydrochloride may has drug interactions.please do inform the doctor about the ongoing medicines when taken with other medication.
Please do inform the treating physician if there is any of the following accompanying conditions
Respiratory or Cardiovascular problems disorders
Enlarged Prostate & urinary problems
Urinary disorder or enlarged prostate
Gastro Intestinal problems
As Meclizine is avoided during these disorders as it can aggravate the pre existing disease &/ or interfere with the drugs advised in treating these conditions
Meclizine in Vestibular Disorders
Meclizine Hydrochloride acts by depressing the central nervous system & reduces over activity of vestibular system . In acute vertiginous episode symptoms like nausea & vertigo.
The drug has usually prescribed during acute episode for not more than 3-5 days and is to be discontinued soon the complaints have subsided.
If symptoms of vertigo persist Complete Assesment of Vestibular System is suggested and rehabilitation may be needed
Recommended in patients having Labyrinthitis ,Vestibular Neuritis and acute exacerbation in Meniere’s Disease.